9,589 research outputs found

    Ol′ga Berggol′ts After the War: a Pre-Emptive Response to Zhdanov

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    This is the final version. Available from Modern Humanities Research Association and JSTOR via the links in this recordThere is another ORE record for this publication: http://hdl.handle.net/10036/40153An article on Akhmatova's war poetry, written by Berggol'ts in 1946 but unpublished until 2001, argues that the war has changed people's perspectives and challenges standard Soviet attitudes towards Akhmatova, calling for an objective reappraisal of art and literature since 1900. Berggol'ts's defence of Akhmatova's love poetry is explored in relation to her own writing on the theme, and her arguments in favour of poetic integrity and autonomy are also shown to have a particularly personal resonance. In writing about Akhmatova, Berggol'ts expressed her own understanding of her role as a poet, ideas which would resurface in her own poetry and criticism of the 1950s

    Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion

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    Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that suppression of the outer layer COPII component, Sec13, in zebrafish embryos results in a disorganized gut epithelium. In human intestinal epithelial cells (Caco-2), Sec13 depletion causes defective epithelial polarity and organization on permeable supports. Defects are seen in the ability of cells to adhere to the substrate, form a monolayer and form intercellular junctions. When embedded in a three-dimensional matrix, Sec13-depleted Caco-2 cells form cysts but, unlike controls, are defective in lumen expansion. Incorporation of primary fibroblasts within the three-dimensional culture substantially restores normal morphogenesis. We conclude that efficient COPII-dependent secretion, notably assembly of Sec13–Sec31, is required to drive epithelial morphogenesis in both two- and three-dimensional cultures in vitro, as well as in vivo. Our results provide insight into the role of COPII in epithelial morphogenesis and have implications for the interpretation of epithelial polarity and organization assays in cell culture

    Post-16 Curriculum and Qualifications Reform in England and Scotland: lessons from home international comparisons

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    In this article we compare Curriculum 2000 and Higher Still, recent reforms of post-16 education in England and Scotland respectively. We draw on current and earlier research on the unification of academic and vocational learning in England, Scotland and other European countries in order to suggest areas for mutual learning to inform future curriculum and qualifications reform north and south of the Border. We highlight five of these - the conduct of the policy process, issues of progression, assessment, approaches to vocational education and key/core skills. In our conclusion we speculate on the possibility of either convergence or divergence of the English and Scottish upper secondary education systems as both evolve

    ‘Drone’: technically correct, popularly accepted, socially acceptable

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    The Journal of Unmanned Vehicle Systems—led by its founding editor, David Bird—published its first issue in December 2013. It was the first peer-reviewed scientific journal entirely dedicated to research relating to all types of remotely piloted or autonomous robotic vehicles, including those that operate in the air, on the ground, or on or below the water’s surface. Although rare currently, it could also expand to include those that operate in outer space environments (Potter 2020). This is a uniquely eclectic field of research that encompasses multiple engineering and design aspects of the vehicles themselves in addition to a diverse and ever-growing array of practical applications of the technology..

    Restrictive and expansive policy learning – challenges and strategies for knowledge exchange in upper secondary education across the four countries of the UK

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    This article examines the challenges and possibilities for UK policy learning in relation to upper secondary education (USE) across England, Scotland, Wales and Northern Ireland (NI) within current national and global policy contexts. Drawing on a range of international literature, the article explores the concepts of ‘restrictive’ and ‘expansive’ policy learning and develops a framework of dimensions for examining what is taking place across the UK at a time of change for all four national USE systems. From an examination of recent national policy literatures and interviews with key policy actors within the ‘UK laboratory’, we found that the conditions for expansive policy learning had markedly deteriorated due to ‘accelerating divergence’ between the three smaller countries and a dominant England that has been pursuing an ‘extreme Anglo Saxon education model’. The article also notes that some aspects of policy learning continue to take place ‘beneath the radar’ between UK and wide civil society organisations. This activity is more prevalent across the three smaller countries although each, to differing degrees, is still constrained by its position in relation to the UK as a whole

    The evolution of social ecosystem thinking: its relevance for education, economic development and localities

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    This stimulus paper explores the concept of 'social ecosystems' as a way of understanding the dynamics of local economic and skills development. The paper draws on a range of international sources

    Education, skills and employment in East London: an ecosystem analysis

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    This is the first research report of the East London Vocational Education and Training Project (ELVET) that explores FE college/employer forms of collaboration. It contains an overview of economic, social and educational developments across London and then focused on East London. and the four hubs comprising New City College, Newham College and Barking and Dagenham College. In this sub-regional context the report develops an ecosystem analysis in order to identify the key dynamics of the locality
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